GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs2143950 | 1 | rs941653 | chr14:35592538 | PPP2R3C | chr14:35554679-35591679:- | 0.25 | 4.67 | 9.75E-6 | Atopic dermatitis |
| THYM | cis | rs9425766 | 1 | rs9425766 | chr1:173853127 | SERPINC1 | chr1:173872943-173886516:- | 0.55 | 5.57 | 2.4E-7 | Life satisfaction |
| THYM | cis | rs2275426 | 1 | rs9429183 | chr1:46524582 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -6 | 3.55E-8 | Body mass index |
| THYM | cis | rs9362426 | 1 | rs9450662 | chr6:88088593 | C6orf164 | chr6:88032306-88109459:+ | -0.49 | -4.91 | 3.8E-6 | Depressive episodes in bipolar disorder |
| THYM | cis | rs9457247 | 1 | rs9457247 | chr6:167392174 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs9473555 | 1 | rs9463473 | chr6:49380121 | CENPQ | chr6:49431096-49460820:+ | -0.24 | -4.37 | 3.16E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9473555 | 1 | rs9463473 | chr6:49380121 | MUT | chr6:49398994-49431031:- | 0.27 | 4.32 | 3.89E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9473555 | 1 | rs9463474 | chr6:49380199 | CENPQ | chr6:49431096-49460820:+ | -0.24 | -4.37 | 3.16E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9473555 | 1 | rs9463474 | chr6:49380199 | MUT | chr6:49398994-49431031:- | 0.27 | 4.32 | 3.89E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9473555 | 1 | rs9463475 | chr6:49380899 | CENPQ | chr6:49431096-49460820:+ | 0.24 | 4.37 | 3.16E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9473555 | 1 | rs9463475 | chr6:49380899 | MUT | chr6:49398994-49431031:- | -0.27 | -4.32 | 3.89E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9473555 | 1 | rs9463477 | chr6:49386446 | CENPQ | chr6:49431096-49460820:+ | -0.24 | -4.37 | 3.16E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9473555 | 1 | rs9463477 | chr6:49386446 | MUT | chr6:49398994-49431031:- | 0.27 | 4.32 | 3.89E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9369898 | 1 | rs9463478 | chr6:49386564 | CENPQ | chr6:49431096-49460820:+ | -0.3 | -5.65 | 1.67E-7 | Homocysteine levels |
| THYM | cis | rs9473555 | 1 | rs9463479 | chr6:49393275 | CENPQ | chr6:49431096-49460820:+ | -0.24 | -4.37 | 3.16E-5 | Folate pathway vitamin levels |